Prolotherapy, also known as sclerotherapy or reconstructive therapy, is the therapeutic process of injecting a proliferate agent into connective tissues, mostly ligaments, tendons and fascia, to create a controlled, localized inflammatory reaction. Inflammation triggers a healing reaction, inducing proliferation of fibroblasts and new collagen production. This process significantly increases the mass of the connective tissue, which, by becoming stronger and more elastic, normalizes the biomechanics of the spinal segments.
The term prolotherapy was popularized by Dr. Hackett, a physician from Canton, Ohio in the mid-1950s.
- Indications for prolotherapy include:
- Facet joint instability, associated with scoliosis, osteoarthritis, compression fracture or spondylolisthesis
- Laxity of the ligaments of the spine
- Chronic pain associated with stiffness of posture, etc.